Computational tumor stroma reaction evaluation led to novel prognosis-associated fibrosis and molecular signature discoveries in high-grade serous ovarian carcinoma

BackgroundAs one of the key criteria to differentiate benign vs.malignant tumors in ovarian and other solid cancers, tumor-stroma reaction (TSR) is long observed by pathologists and has been found correlated with patient prognosis.However, paucity of study aims to overcome subjective bias or automate TSR evaluation for enabling association analysis

read more